Open AccessNovel Hormone Receptors Present in Apocrine Cystadenoma of the Eyelid
Author(s) -
Sarah E. Brown,
Alan H. Friedman,
Robert Phelps,
Ira J. Bleiweiss,
Albert Y. Wu
Publication year - 2017
Publication title -
ophthalmic plastic and reconstructive surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.528
H-Index - 56
eISSN - 1537-2677
pISSN - 0740-9303
DOI - 10.1097/iop.0000000000000416
Subject(s) - medicine , apocrine , pathology , eyelid , immunohistochemistry , cystadenoma , chromogranin a , surgery , pancreas
A 53-year-old woman presented with an apocrine cystadenoma of the right upper eyelid. Histologic examination revealed proliferating epithelial cells with apocrine snouts and occasional mitotic figures. Immunohistochemical analysis revealed a Ki-67 index of 15% and positive staining for synaptophysin, chromogranin, estrogen receptor, progesterone receptor, gross cystic disease fluid protein (GCDFP)-15, and mammoglobin. The complement of positive immunomarkers in this case reinforces the importance of total excision and careful histologic assessment.