Open AccessCarriage-Associated Streptocccus pneumoniae Serotype 1 in Brussels, Belgium
Author(s) -
Sarah Jourdain,
Pierre Luc Dreze,
Jan Verhaegen,
Laurence Van Melderen,
Pierre Smeesters
Publication year - 2013
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0b013e3182755cb7
Subject(s) - carriage , serotype , multilocus sequence typing , streptococcus pneumoniae , virology , biology , microbiology and biotechnology , typing , pneumococcal infections , population , pneumococcal disease , antibiotics , medicine , genotype , genetics , environmental health , gene , pathology
Streptococcus pneumoniae serotype 1 presents a high invasiveness index and is seldom isolated from its niche, the nasopharynx. We report an unusual serotype 1 carriage in a healthy pediatric population at the time of the heptavalent pneumococcal vaccine adoption in Belgium. Our sampling period coincides with an epidemic wave of serotype 1 invasive pneumococcal infections. Invasive and colonizing isolates were characterized by both antibiotic resistance profile and multilocus sequence typing and were shown to share the same backbone (ST306 and ST350).