Open AccessAnti-N-methyl D-Aspartate Receptor Encephalitis Mimics Viral Encephalitis
Author(s) -
Mustafa R. Bseikri,
Jubilee Barton,
Julie A. Kulhanjian,
Josep Dalmau,
Ronald A. Cohen,
Carol Glaser,
Arup Roy-Burman
Publication year - 2012
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0b013e31823d52eb
Subject(s) - encephalitis , viral encephalitis , autoimmune encephalitis , medicine , autoantibody , immune system , virology , immunology , virus , antibody
We describe the clinical courses of 3 children with a psychochoreiform encephalitis associated with anti-N-methyl D-aspartate receptor autoantibodies. These cases, including the most severely medically complicated survivor to date, illustrate the challenges of diagnosis, supportive care, and immune-modulating therapy. Clinical and laboratory features are similar to those of viral encephalitis, and the condition is often reversible with appropriate diagnosis and treatment.