Open AccessUNDERLYING CONDITIONS IN CHILDREN WITH INVASIVE PNEUMOCOCCAL DISEASE IN THE CONJUGATE VACCINE ERA
Author(s) -
Katherine Hsu,
Kimberly M. Shea,
Abbie E. Stevenson,
Stephen I. Pelton
Publication year - 2011
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0b013e3181fab1cf
Subject(s) - medicine , immunosuppression , pneumococcal conjugate vaccine , pneumonia , asthma , disease , pneumococcal vaccine , pediatrics , pneumococcal disease , conjugate vaccine , immunology , intensive care medicine , streptococcus pneumoniae , antibiotics , immunization , immune system , microbiology and biotechnology , biology
We analyzed characteristics of invasive pneumococcal disease cases occurring in Massachusetts after the introduction and use of conjugate vaccine by underlying risk. Among 578 cases with sufficient information, 16% had high-risk or presumed high-risk conditions (HR/PHR), 3% had asthma, and 80% had no known risk (NKR). The most common HR/PHR conditions were disorders associated with immunosuppression. HR/PHR cases tended to be older and were more likely to be hospitalized than were children with NKR. Children with asthma presented with pneumonia more often than children with NKR.