Open AccessCLINICAL PERFORMANCE OF A RAPID INFLUENZA TEST AND COMPARISON OF NASAL VERSUS THROAT SWABS TO DETECT 2009 PANDEMIC INFLUENZA A (H1N1) INFECTION IN THAI CHILDREN
Author(s) -
Piyarat Suntarattiwong,
Richard G. Jarman,
Jens Levy,
Henry C. Baggett,
Robert V. Gibbons,
Tawee Chotpitayasudh,
James Mark Simmerman
Publication year - 2010
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0b013e3181c6f05c
Subject(s) - medicine , throat , confidence interval , polymerase chain reaction , reverse transcription polymerase chain reaction , pandemic influenza , pandemic , virology , pcr test , influenza like illness , virus , covid-19 , immunology , surgery , biology , disease , infectious disease (medical specialty) , gene , biochemistry , messenger rna
We identified febrile pediatric outpatients seeking care for influenza like illness in Bangkok. Two nasal and 1 throat swab were tested using the QuickVue A+B rapid influenza kit and reverse transcription-polymerase chain reaction. Among 142 pandemic influenza A (H1N1)-positive patients, the QuickVue test identified 89 positive tests for a sensitivity of 62.7% (95% confidence interval [CI]: 54.7-70.6). Specificity was 99.2% (95% CI: 98-100). In the 0 to 2 years age group, sensitivity was 76.7% (95% CI: 61.5-91.8). Throat and nasal swabs are equally useful diagnostic specimens for reverse transcription-polymerase chain reaction diagnosis.