Open AccessSARS-CoV-2 Infection in an Adolescent With X-linked Agammaglobulinemia
Author(s) -
Noella Maria Delia Pereira,
Paul T. Heath,
Katja Doerholt,
Andres Fernando Almario-Hernandez,
Clare Gilmour,
Simon B. Drysdale
Publication year - 2021
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000003360
Subject(s) - bronchoalveolar lavage , medicine , covid-19 , erythrocyte sedimentation rate , immunology , pediatrics , disease , virology , infectious disease (medical specialty) , lung
We present a case of a 17-year-old boy with X-linked agammaglobulinemia who had mild disease when initially infected with SARS-CoV-2 but after recovering from acute infection developed fevers and a raised erythrocyte sedimentation rate that persisted for several weeks without any ongoing respiratory symptoms. Multiple nasopharyngeal swabs were found to be negative for SARS-CoV-2 during the febrile period, but typical changes of COVID-19 on high resolution CT chest scan led to the detection of SARS-CoV-2 on RT-PCR in a sample from a bronchoalveolar lavage. His fevers completely resolved after a 5-day course of remdesivir.