Open AccessLow Pretreatment Viral Loads in Infants With HIV in an Era of High-maternal Antiretroviral Therapy Coverage
Author(s) -
Faeezah Patel,
Stephanie Shiau,
Renate Strehlau,
Yanhan Shen,
Megan Burke,
Maria Paximadis,
Sharon Shalekoff,
Diana B. Schramm,
Karl-Günter Technau,
Gayle Sherman,
Ashraf Coovadia,
Caroline T. Tiemessen,
Elaine J. Abrams,
Louise Kuhn
Publication year - 2020
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000002897
Subject(s) - medicine , interquartile range , nevirapine , viral load , odds ratio , confidence interval , antiretroviral therapy , pediatrics , pregnancy , obstetrics , human immunodeficiency virus (hiv) , immunology , biology , genetics
With expansion of antiretroviral therapy (ART) programs, transmission rates are low but new infant infections still occur. We investigated predictors of pre-ART viral load (VL) and CD4+ T-cell counts and percentages in infants diagnosed with HIV at birth in a setting with high coverage of maternal ART and infant prophylaxis.