Open AccessPediatric Inflammatory Multisystem Syndrome With Central Nervous System Involvement and Hypocomplementemia Following SARS-COV-2 Infection
Author(s) -
Tslil Regev,
Maayan Antebi,
Danny Eytan,
Yael Shachor-Meyouhas,
Anat Ilivitzki,
Yonatan Butbul Aviel,
Josef BenAri
Publication year - 2020
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000002804
Subject(s) - medicine , kawasaki disease , vasculitis , central nervous system , disease , coronavirus , multisystem disease , immunology , covid-19 , respiratory system , pathology , infectious disease (medical specialty) , artery
Pediatric inflammatory multisystem syndromes associated with Severe Acute Respiratory Syndrome Coronavirus 2 are emerging in recent reports. We describe a patient with critical illness consistent with atypical Kawasaki disease with cardiac dysfunction and abdominal involvement presenting weeks after Severe Acute Respiratory Syndrome Coronavirus 2 infection. Our patient showed unique central nervous system involvement with small vessel vasculitis and profound hypocomplementemia, both not previously reported in case descriptions and may hint at possible disease mechanisms.