Open AccessHospital-acquired Pneumonia and Ventilator-associated Pneumonia in Children
Author(s) -
Jessica E. Ericson,
John K. McGuire,
Marian G. Michaels,
Adam Schwarz,
Robert W. Frenck,
Jaime G. Deville,
Swati Agarwal,
Adam Bressler,
Junheng Gao,
Tracy Spears,
Daniel K. Benjamin,
Paul Smith,
John S. Bradley
Publication year - 2020
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000002642
Subject(s) - medicine , pneumonia , incidence (geometry) , intensive care medicine , odds ratio , sepsis , epidemiology , hospital acquired pneumonia , mechanical ventilation , antibiotics , intensive care , medical record , respiratory tract infections , clinical trial , pediatrics , emergency medicine , respiratory system , biology , microbiology and biotechnology , physics , optics
Clinical trials for antibiotics designed to treat hospital-acquired and ventilator-associated bacterial pneumonias (HABP/VABP) are hampered by making these diagnoses in a way that is acceptable to the United States Food and Drug Administration and consistent with standards of care. We examined laboratory and clinical features that might improve pediatric HABP/VABP trial efficiency by identifying risk factors predisposing children to HABP/VABP and describing the epidemiology of pediatric HABP/VABP.