Open AccessImmunogenicity of Diphtheria Booster Vaccination in Adolescents With Inflammatory Bowel Disease
Author(s) -
Łukasz Dembiński,
Elżbieta Krzesiek,
Beata Klincewicz,
Urszula Grzybowska-Chłebowczyk,
Urszula Demkow,
Aleksandra Banaszkiewicz,
Andrzej Radzikowski
Publication year - 2020
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000002547
Subject(s) - medicine , immunogenicity , inflammatory bowel disease , booster (rocketry) , immunosuppression , diphtheria , vaccination , adverse effect , diphtheria toxin , immunology , disease , pediatrics , immune system , physics , astronomy , toxin , biochemistry , chemistry
The aim of this prospective study was to assess the immunogenicity and safety of booster vaccine against diphtheria in children with inflammatory bowel disease on and without immunosuppression treatment. Immunoprotection was achieved in 93% of the children. No significant differences depending on the treatment used and no serious adverse events or flares of inflammatory bowel disease were observed.