Open AccessA Pharmacoepidemiologic Study of the Safety and Effectiveness of Clindamycin in Infants
Author(s) -
Rachel G. Greenberg,
Huali Wu,
Anil Maharaj,
Michael CohenWolkowiez,
Kay M. Tomashek,
Blaire L. Osborn,
Reese H. Clark,
Emmanuel B. Walter
Publication year - 2020
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000002524
Subject(s) - clindamycin , medicine , bacteremia , odds ratio , neonatal intensive care unit , adverse effect , retrospective cohort study , gestational age , neonatal sepsis , pediatrics , sepsis , antibiotics , pregnancy , genetics , microbiology and biotechnology , biology
Despite the absence of adequate safety or efficacy data, clindamycin is widely prescribed in the neonatal intensive care unit. We evaluated the association between clindamycin exposure and adverse events, as well as antibiotic effectiveness in infants.