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Long-term Vaccine Impact on Invasive Pneumococcal Disease Among Children With Significant Comorbidities in a Large Australian Birth Cohort
Author(s) -
Sanjay Jayasinghe,
Bette Liu,
Heather Gidding,
Amy Gibson,
Clayton Chiu,
Peter McIntyre
Publication year - 2019
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000002407
Subject(s) - medicine , cohort , confidence interval , incidence (geometry) , hazard ratio , pediatrics , pneumococcal conjugate vaccine , population , cohort study , retrospective cohort study , relative risk , streptococcus pneumoniae , environmental health , biology , bacteria , optics , genetics , physics
Little is known about long-term invasive pneumococcal disease (IPD) incidence in children with risk factors (RFs) in populations with high coverage pneumococcal conjugate vaccine (PCV) programs. We measured IPD burden and changes with PCV use in children by RF status.