Open AccessCongenital Cytomegalovirus and Neonatal Herpes Simplex Virus Infections: To Treat or Not to Treat?
Author(s) -
Richard J. Whitley
Publication year - 2019
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000002325
Subject(s) - valganciclovir , cytomegalovirus , ganciclovir , medicine , sensorineural hearing loss , asymptomatic , pediatrics , herpes simplex virus , disease , hearing loss , herpesviridae , virus , virology , human cytomegalovirus , viral disease , audiology
Congenital cytomegalovirus infections are among the most common of the newborn in the developed world. These infections are the most common cause of sensorineural hearing loss. Studies utilizing ganciclovir and valganciclovir demonstrate improved hearing and Bailey Developmental scores. Because of the ease of administration, valganciclovir is the recommended treatment of choice for 6 months. Therapy should be reserved for those babies with symptomatic disease; no data are available regarding the impact of treatment on those babies with asymptomatic disease.