Open AccessSpecimen Pooling as a Diagnostic Strategy for Microbiologic Confirmation in Children with Intrathoracic Tuberculosis
Author(s) -
Elisabetta Walters,
Marieke M. van der Zalm,
Anne-Marie Demers,
Andrew Whitelaw,
Megan Palmer,
Corné Bosch,
Heather R. Draper,
H. Simon Schaaf,
Pierre Goussard,
Carl Lombard,
Robert Gie,
Anneke C. Hesseling
Publication year - 2019
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000002240
Subject(s) - medicine , tuberculosis , sputum , pulmonary tuberculosis , surgery , gastroenterology , pathology
Three-hundred four young children with suspected pulmonary tuberculosis had a gastric aspirate, induced sputum and nasopharyngeal aspirate collected on each of 2 consecutive weekdays. Specimens collected on the second day were pooled in the laboratory for each child individually. The diagnostic yield by Xpert and culture from pooled specimens was not significantly different to a single gastric aspirate.