Open AccessAntibody Persistence up to 3 Years After Primary Immunization With Inactivated Japanese Encephalitis Vaccine IXIARO in Philippine Children and Effect of a Booster Dose
Author(s) -
Vera Kadlecek,
Charissa Borja-Tabora,
Susanne Eder-Lingelbach,
Salvacion Gatchalian,
Sigrid Kiermayr,
Benjamin Sablan,
Michael Kundi,
Christian Taucher,
Katrin Dubischar
Publication year - 2018
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000002124
Subject(s) - booster dose , immunization , persistence (discontinuity) , booster (rocketry) , virology , japanese encephalitis vaccine , antibody , medicine , japanese encephalitis , encephalitis , immunology , pediatrics , virus , physics , astronomy , geotechnical engineering , engineering
An inactivated Vero cell culture derived Japanese encephalitis virus vaccine (IXIARO) requires a booster dose 1 year after primary schedule for long-term antibody persistence in adults. The aim of this study is to evaluate immunogenicity and safety of a booster dose in children 2 months to <18 years of age.