Open AccessEvaluation of the Influence of Gastrointestinal Coinfections on Rotavirus Vaccine Effectiveness in Botswana
Author(s) -
Margaret Mokomane,
Jacqueline E. Tate,
Andrew P. Steenhoff,
Mathew D. Esona,
Michael D. Bowen,
Kwana Lechiile,
Jeffrey M. Pernica,
Ishmael Kasvosve,
Umesh D. Parashar,
David M. Goldfarb
Publication year - 2018
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000001828
Subject(s) - rotavirus , coinfection , rotavirus vaccine , medicine , diarrhea , virology , confidence interval , immunology , virus
Studies have demonstrated reduced rotavirus vaccine effectiveness (VE) in resource-limited settings. Enteropathogen coinfections in rotavirus cases have been hypothesized to contribute to the lower VE in such settings. We sought to determine if coinfections affect rotavirus VE in Botswana.