Open AccessCharacteristics and Outcomes OF Acute Otitis Media in Children Carrying Streptococcus Pneumoniae or Haemophilus Influenzae in Their Nasopharynx as a Single Otopathogen After Introduction of the Heptavalent Pneumococcal Conjugate Vaccine
Author(s) -
Laurence Caeymaex,
Emmanuelle Varon,
Corinne Lévy,
Stéphane Béchet,
Véronique Derkx,
V Desvignes,
Catherine Doit,
Robert Cohen
Publication year - 2014
Publication title -
the pediatric infectious disease journal/the pediatric infectious disease journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.028
H-Index - 140
eISSN - 1532-0987
pISSN - 0891-3668
DOI - 10.1097/inf.0000000000000213
Subject(s) - medicine , streptococcus pneumoniae , haemophilus influenzae , odds ratio , otitis , confidence interval , pneumococcal conjugate vaccine , serotype , acute otitis media , pneumococcal infections , pasteurellaceae , immunology , microbiology and biotechnology , surgery , antibiotics , biology
After PCV7 implementation, clinical characteristics were investigated in 832 young children with acute otitis media, carrying a single S. pneumoniae or H. influenzae in their nasopharynx. As compared with H. influenzae, S. pneumoniae-associated acute otitis media was less frequently associated with treatment failure (odds ratio = 0.5; 95% confidence interval: 0.36-0.83) and recurrence (odds ratio = 0.4; 95% confidence interval: 0.22-0.75). Post-PCV7 serotype replacement seemed not to affect the acute otitis media characteristics in these children.