Open AccessJuvenile Open-angle Glaucoma With Waardenburg Syndrome: A Case Report
Author(s) -
Ahmed Abdelrahman,
Rana Hussein Amin
Publication year - 2020
Publication title -
journal of glaucoma
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.11
H-Index - 88
eISSN - 1536-481X
pISSN - 1057-0829
DOI - 10.1097/ijg.0000000000001676
Subject(s) - medicine , glaucoma , waardenburg syndrome , juvenile , neural crest , ophthalmology , intraocular pressure , genetics , biology , embryo , gene , phenotype
Waardenburg syndrome (WS) is a genetic disorder resulting in anomalies of derivatives of neural crest cells during development. Patients tend to have variable degrees of pigmentary defects affecting skin, hair, and irides in addition to hearing loss and possible systemic neurological associations. Elevation of the intraocular pressure has been reported in several adult patients with WS. We report the first case of WS to be associated with juvenile open-angle glaucoma in a 20-year-old Egyptian man thus expanding the spectrum of the types of glaucoma that can coexist with the syndrome.