Open AccessFLUORESCENCE LIFETIME IMAGING OPHTHALMOSCOPY (FLIO) PATTERNS IN CLINICALLY UNAFFECTED CHILDREN OF MACULAR TELANGIECTASIA TYPE 2 (MACTEL) PATIENTS
Author(s) -
Lydia Sauer,
Alexandra Vitale,
Karl Andersen,
Barbara Hart,
Paul S. Bernstein
Publication year - 2020
Publication title -
retina
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.24
H-Index - 120
eISSN - 1539-2864
pISSN - 0275-004X
DOI - 10.1097/iae.0000000000002646
Subject(s) - macular telangiectasia , ophthalmoscopy , optical coherence tomography , penetrance , fluorescein angiography , retinal , medicine , fluorescence lifetime imaging microscopy , ophthalmology , pathology , fluorescence , biology , optics , genetics , gene , physics , phenotype
Macular telangiectasia Type 2 (MacTel) is an inherited retinal disease following an autosomal dominant pattern with late onset and reduced penetrance. Fluorescence lifetime imaging ophthalmoscopy (FLIO) enhances diagnosis by showing distinct changes in MacTel. This study investigates FLIO-associated changes in clinically unaffected family members.