Open AccessRisk and Response Adapted Treatment Guidelines for Managing First Relapsed and Refractory Classical Hodgkin Lymphoma in Children and Young People. Recommendations from the EuroNet Pediatric Hodgkin Lymphoma Group
Author(s) -
Daw Stephen,
Hasenclever Dirk,
Mascarin Maurizio,
FernándezTeijeiro Ana,
Balwierz Walentyna,
Beishuizen Auke,
Burnelli Roberta,
Cepelova Michaela,
Claviez Alexander,
Dieckmann Karin,
LandmanParker Judith,
Kluge Regine,
Körholz Dieter,
MauzKörholz Christine,
Wallace William Hamish,
Leblanc Thierry
Publication year - 2020
Publication title -
hemasphere
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.677
H-Index - 11
ISSN - 2572-9241
DOI - 10.1097/hs9.0000000000000329
Subject(s) - medicine , salvage therapy , guideline , lymphoma , refractory (planetary science) , hodgkin lymphoma , chemotherapy , oncology , hodgkin's lymphoma , pathology , physics , astrobiology
The objective of this guideline is to aid clinicians in making individual salvage treatment plans for pediatric and adolescent patients with first relapse or refractory (R/R) classical Hodgkin lymphoma (cHL). While salvage with standard dose chemotherapy followed by high dose chemotherapy and autologous stem cell transplant is often considered the standard of care in adult practice, pediatric practice adopts a more individualized risk stratified and response adapted approach to salvage treatment with greater use of non‐transplant salvage. Here, we present on behalf of the EuroNet Pediatric Hodgkin Lymphoma group, evidence and consensus‐based guidelines for standardized diagnostic, prognostic and response procedures to allocate children and adolescents with R/R cHL to stratified salvage treatments.