Open AccessDisentangling the varying associations between systolic blood pressure and health outcomes in the very old: an individual patient data meta-analysis
Author(s) -
Jonathan Bogaerts,
Rosalinde K. E. Poortvliet,
Veerle M G T H Van Der Klei,
Wilco P. Achterberg,
Jeanet W. Blom,
Ruth Teh,
Marama MuruLanning,
Ngaire Kerse,
Anna Rolleston,
Carol Jagger,
Andrew Kingston,
Louise Robinson,
Yasumichi Arai,
Ryo Shikimoto,
Jacobijn Gussekloo
Publication year - 2022
Publication title -
journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.249
H-Index - 172
eISSN - 1473-5598
pISSN - 0263-6352
DOI - 10.1097/hjh.0000000000003219
Subject(s) - medicine , meta analysis , blood pressure , cardiology
While randomized controlled trials have proven the benefits of blood pressure (BP) lowering in participating octogenarians, population-based observational studies suggest an association between low systolic blood pressure (SBP) and faster overall decline. This study investigates the effects of BP-lowering treatment, a history of cardiovascular diseases (CVD), and cognitive and physical fitness on the associations between SBP and health outcomes in the very old.