Open AccessSeptal curvature as a robust and reproducible marker for basal septal hypertrophy
Author(s) -
Maciej Marciniak,
Andrew Gilbert,
Filip Lončarić,
João Filipe Fernandes,
Bart Bijnens,
Marta Sitges,
Andrew P. King,
F. Crispi,
Pablo Lamata
Publication year - 2021
Publication title -
journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.249
H-Index - 172
eISSN - 1473-5598
pISSN - 0263-6352
DOI - 10.1097/hjh.0000000000002813
Subject(s) - medicine , cardiology , ventricle , basal (medicine) , muscle hypertrophy , reproducibility , interventricular septum , mathematics , statistics , insulin
Basal septal hypertrophy (BSH) is an asymmetric, localized thickening of the upper interventricular septum and constitutes a marker of an early remodelling in patients with hypertension. This morphological trait has been extensively researched because of its prevalence in hypertension, yet its clinical and prognostic value for individual patients remains undetermined. One of the reasons is the lack of a reliable and reproducible metric to quantify the presence and the extent of BSH. This article proposes the use of the curvature of the left ventricular endocardium as a robust feature for BSH characterization, and as an objective criterion to quantify current subjective 'visual assessment' of the presence of sigmoidal septum. The proposed marker, called average septal curvature, is defined as the inverse of the radius adjacent to each point of the endocardial contour along the basal and mid inferoseptal segments of the left ventricle.