Open AccessCirculating senescent angiogenic T cells are linked with endothelial dysfunction and systemic inflammation in hypertension
Author(s) -
Gaoxing Zhang,
Yuanya Liu,
Yumin Qiu,
Jianning Zhang,
Jinhua Sun,
Zhe Zhou,
Zhichao Wang,
Peishan Zeng,
Jun Tao,
Jiang He
Publication year - 2020
Publication title -
journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.249
H-Index - 172
eISSN - 1473-5598
pISSN - 0263-6352
DOI - 10.1097/hjh.0000000000002715
Subject(s) - endothelial dysfunction , medicine , immunophenotyping , cd31 , systemic inflammation , inflammation , endothelial stem cell , immunology , endothelium , cytokine , flow cytometry , biology , immunohistochemistry , biochemistry , in vitro
Angiogenic T cells (Tang cells), a recently discovered T-cell subset, have been reported involved in the repair of endothelial injury. The purpose of this study was to explore the correlation of immunologic senescence and pro-inflammatory capacity of Tang cells with endothelial dysfunction in hypertensive patients.