Open AccessEndovascular reversal of renovascular hypertension blunts cardiac dysfunction and deformation in swine
Author(s) -
Shasha Yu,
Kai Jiang,
Xiang Yang Zhu,
Christopher M. Ferguson,
James D. Krier,
Amir Lerman,
Lilach O. Lerman
Publication year - 2021
Publication title -
journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.249
H-Index - 172
eISSN - 1473-5598
pISSN - 0263-6352
DOI - 10.1097/hjh.0000000000002654
Subject(s) - renovascular hypertension , cardiology , medicine , diastole , cardiac function curve , blood pressure , heart failure
Renovascular hypertension (RVH) induces hemodynamic and humoral aberrations that may impair cardiac function, structure and mechanics, including cardiac twist and deformation. Revascularization of a stenotic renal artery can decrease blood pressure (BP), but its ability to restore cardiac mechanics in RVH remains unclear. We hypothesized that percutaneous transluminal renal angioplasty (PTRA) would improve cardiac function and left ventricular (LV) deformation in swine RVH.