Open AccessThe gut microbiota-related metabolite phenylacetylglutamine associates with increased risk of incident coronary artery disease
Author(s) -
Filip Ottosson,
Louise Brunkwall,
Einar Smith,
Marju OrhoMelander,
Peter M. Nilsson,
Céline Fernandez,
Olle Melander
Publication year - 2020
Publication title -
journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.249
H-Index - 172
eISSN - 1473-5598
pISSN - 0263-6352
DOI - 10.1097/hjh.0000000000002569
Subject(s) - gut flora , medicine , metabolite , coronary artery disease , physiology , prospective cohort study , metabolome , cohort study , endocrinology , immunology
The gut microbiota is increasingly being implicated in cardiovascular health. Metabolites produced by bacteria have been suggested to be mediators in the bacterial action on cardiovascular health. We aimed to identify gut microbiota-related plasma metabolites and test whether these metabolites associate with future risk of coronary artery disease (CAD).