Open AccessImpact of single-pill combination therapy on adherence, blood pressure control, and clinical outcomes: a rapid evidence assessment of recent literature
Author(s) -
Κonstantinos Tsioufis,
Reinhold Kreutz,
Georgia Sykara,
Joris van Vugt,
Tamer Hassan
Publication year - 2020
Publication title -
journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.249
H-Index - 172
eISSN - 1473-5598
pISSN - 0263-6352
DOI - 10.1097/hjh.0000000000002381
Subject(s) - medicine , blood pressure , pill , combination therapy , observational study , medline , cochrane library , randomized controlled trial , pharmacotherapy , physical therapy , intensive care medicine , pharmacology , political science , law
The 2018 European Society of Cardiology/European Society of Hypertension Guidelines for the management of arterial hypertension raised the need for evidence to support the use of single-pill combination (SPC) therapy in preference to free-dosed therapy for hypertension. This systematic rapid evidence assessment sought to determine if initiating SPC therapy improves adherence, blood pressure (BP) control and/or cardiovascular outcomes vs. initiation of free-dose combination therapy.