Open AccessMeasuring LDL-cholesterol: what is the best way to do it?
Author(s) -
Anna Wolska,
Alan T. Remaley
Publication year - 2020
Publication title -
current opinion in cardiology/current opinion in cardiology, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.826
H-Index - 78
eISSN - 1080-787X
pISSN - 0268-4705
DOI - 10.1097/hco.0000000000000740
Subject(s) - ldl cholesterol , hypertriglyceridemia , atherosclerotic cardiovascular disease , medicine , risk assessment , cholesterol , disease , computer science , triglyceride , computer security
Cholesterol on low-density lipoproteins (LDL-C) is one of the main drivers of atherosclerotic cardiovascular disease (ASCVD) and hence its measurement is critical in the management of patients at risk. Although LDL-C has routinely been either calculated by the Friedewald equation or measured with direct assays, these methods have limitations, particularly for patients with dyslipidaemias, low LDL-C, and hypertriglyceridemia. The focus of this review will be recent advances in the measurement of LDL for ASCVD risk management.