Open AccessRisk Factors for Progression From Gestational Diabetes to Postpartum Type 2 Diabetes: A Review
Author(s) -
Angela M. Bengtson,
Sebastián Ramos,
David A. Savitz,
Erika F. Werner
Publication year - 2020
Publication title -
clinical obstetrics and gynecology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.927
H-Index - 75
eISSN - 1532-5520
pISSN - 0009-9201
DOI - 10.1097/grf.0000000000000585
Subject(s) - medicine , gestational diabetes , type 2 diabetes , diabetes mellitus , obstetrics , pregnancy , gestation , endocrinology , genetics , biology
Gestational diabetes mellitus (GDM) complicates 6% to 8% of pregnancies and up to 50% of women with GDM progress to type 2 diabetes mellitus (DM) within 5 years postpartum. Clinicians have little guidance on which women are most at risk for DM progression or when evidence-based prevention strategies should be implemented in a woman's lifecycle. To help address this gap, the authors review identifiable determinants of progression from GDM to DM across the perinatal period, considering prepregnancy, pregnancy, and postpartum periods. The authors categorize evidence by pathways of risk including genetic, metabolic, and behavioral factors that influence progression to DM among women with GDM.