Open AccessLymphoepithelioma-like Carcinoma of the Skin
Author(s) -
C Lassen,
Jørgen LockAndersen
Publication year - 2014
Publication title -
plastic and reconstructive surgery. global open
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.759
H-Index - 28
ISSN - 2169-7574
DOI - 10.1097/gox.0000000000000215
Subject(s) - lymphoepithelioma like carcinoma , lymphoepithelioma , medicine , actinic keratosis , carcinoma , basal cell carcinoma , pathology , adjuvant radiotherapy , dermatology , perineural invasion , basal cell , nasopharyngeal carcinoma , radiation therapy , cancer , epstein–barr virus , virus , virology
Summary: Lymphoepithelioma-like carcinoma of the skin is a rare, low malignant cutaneous neoplasm. We report a case of an elderly woman with lymphoepithelioma-like carcinoma of the skin in the forehead. The tumor was mistaken first as actinic keratosis and later as metastatic squamous cell carcinoma. A histological reassessment showed lymphoepithelioma-like carcinoma of the skin with perineural invasion, which is rare and considered more aggressive. The patient therefore received adjuvant radiotherapy after the recommended wide excision. Lymphoepithelioma-like carcinoma of the skin is a variant of squamous cell carcinoma, and histologically, it resembles the more aggressive lymphoepithelioma of the nasopharynx. The later is Epstein-Barr positive, whereas lymphoepithelioma-like carcinoma normally is not. Lymphoepithelioma-like carcinoma is an important diagnosis to know and the disease is discussed