Open AccessGenetic variants predictive of reproductive aging are associated with vasomotor symptoms in a multiracial/ethnic cohort
Author(s) -
Wei Zhao,
Jennifer A. Smith,
Miao Yu,
Carolyn Crandall,
Rebecca C. Thurston,
Michelle Hood,
Edward A. Ruiz-Narváez,
Patricia A. Peyser,
Sharon L. R. Kardia,
Sioḃán D. Harlow
Publication year - 2021
Publication title -
menopause
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.086
H-Index - 103
eISSN - 1530-0374
pISSN - 1072-3714
DOI - 10.1097/gme.0000000000001785
Subject(s) - menarche , medicine , cohort , demography , minor allele frequency , menopause , single nucleotide polymorphism , odds ratio , gynecology , genotype , genetics , gene , sociology , biology
Vasomotor symptoms (VMS), hot flashes, and night sweats are cardinal symptoms of the menopausal transition. Little is known about genetic influences on VMS. This study evaluated whether previously identified genetic factors predictive of VMS, age at menarche, and age at menopause were associated with VMS in a multiracial/ethnic cohort.