Open AccessApolipoprotein E4 genotype in combination with poor metabolic profile is associated with reduced cognitive performance in healthy postmenopausal women: implications for late onset Alzheimer's disease
Author(s) -
Roksana Karim,
Melissa Koç,
Jamaica R. Rettberg,
Howard N. Hodis,
Victor W. Henderson,
Jan A. St. John,
Hooman Allayee,
Roberta Dı́az Brinton,
Wendy J. Mack
Publication year - 2019
Publication title -
menopause
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.086
H-Index - 103
eISSN - 1530-0374
pISSN - 1072-3714
DOI - 10.1097/gme.0000000000001160
Subject(s) - medicine , postmenopausal women , effects of sleep deprivation on cognitive performance , alzheimer's disease , cognition , disease , apolipoprotein e , metabolic syndrome , cognitive decline , apolipoprotein b , endocrinology , gerontology , physiology , dementia , psychiatry , obesity , cholesterol
We hypothesized the association of metabolic profile on cognition in postmenopausal women will be greater among ApoE4 carriers compared with noncarriers.