Open AccessDeep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer
Author(s) -
James N. Ingle,
Krishna R. Kalari,
Yukihide Momozawa,
Michiaki Kubo,
Yoichi Furukawa,
Lois E. Shepherd,
Matthew J. Ellis,
Paul E. Goss,
Poulami Barman,
Erin E. Carlson,
Jason P. Sinnwell,
Xiaojia Tang,
Matthew P. Goetz,
Bingshu E. Chen,
Junmei Cairns,
Richard M. Weinshilboum,
Liewei Wang
Publication year - 2019
Publication title -
pharmacogenetics and genomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.579
H-Index - 140
eISSN - 1744-6880
pISSN - 1744-6872
DOI - 10.1097/fpc.0000000000000382
Subject(s) - genome wide association study , breast cancer , exemestane , single nucleotide polymorphism , haplotype , snp , genetic association , oncology , medicine , genetics , biology , cancer , tamoxifen , allele , genotype , gene
To identify additional genetic variants beyond those observed in a previous genome-wide association study (GWAS) in women treated on the MA.27 clinical trial in which women were randomized to 5 years of adjuvant therapy with anastrozole or exemestane.