Open AccessGenetic variations associated with gemcitabine treatment outcome in pancreatic cancer
Author(s) -
Liang Li,
Jian Wei Zhang,
Gregory D. Jenkins,
Fang Xie,
Erin E. Carlson,
Brooke L. Fridley,
William R. Bamlet,
Gloria M. Petersen,
Robert R. McWilliams,
Liewei Wang
Publication year - 2016
Publication title -
pharmacogenetics and genomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.579
H-Index - 140
eISSN - 1744-6880
pISSN - 1744-6872
DOI - 10.1097/fpc.0000000000000241
Subject(s) - gemcitabine , pancreatic cancer , single nucleotide polymorphism , oncology , biology , medicine , genotyping , genotype , cancer , genetics , gene
Pancreatic cancer is a rapidly fatal disease with gemcitabine remaining the first-line therapy. We performed a genotype-phenotype association study to identify biomarkers for predicting gemcitabine treatment outcome.