Open AccessEffects of Prostaglandin E1 on Vascular ATP-Sensitive Potassium Channels
Author(s) -
Satoru Eguchi,
Takashi Kawano,
Yinhua Yinhua,
Katsuya Tanaka,
Sonoko Yasui,
Kazuaki Mawatari,
Akira Takahashi,
Yutaka Nakaya,
Shuzo Oshita,
Nobuyoshi Nakajo
Publication year - 2007
Publication title -
journal of cardiovascular pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.762
H-Index - 100
eISSN - 1533-4023
pISSN - 0160-2446
DOI - 10.1097/fjc.0b013e3181583d9b
Subject(s) - glibenclamide , prostaglandin e1 , vascular smooth muscle , potassium channel , chemistry , isometric exercise , atp sensitive potassium channel , electrophysiology , patch clamp , prostaglandin , pharmacology , protein kinase a , biophysics , medicine , endocrinology , biochemistry , biology , smooth muscle , enzyme , diabetes mellitus
Prostaglandin E1 (PGE1) has been reported to activate ATP-sensitive potassium (KATP) channels, which induces vasorelaxation. However, direct evidence of PGE1 interactions with vascular KATP channels is limited.