Open AccessA nebulised antitumour necrosis factor receptor-1 domain antibody in patients at risk of postoperative lung injury: A randomised, placebo-controlled pilot study
Author(s) -
James Ryan,
Andrew I. Bayliffe,
Daniel F McAuley,
Joyce Yeung,
David Thickett,
Phillip A Howells,
Ciara O’Donnell,
Arlette Vassallo,
Tracey J. Wright,
Elizabeth McKie,
Kelly Hardes,
Charlotte Summers,
M. Shields,
William Powley,
Robert Wilson,
Aili L. Lazaar,
Andrew Fowler,
Gavin D. Perkins
Publication year - 2020
Publication title -
european journal of anaesthesiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.445
H-Index - 76
eISSN - 1365-2346
pISSN - 0265-0215
DOI - 10.1097/eja.0000000000001245
Subject(s) - medicine , placebo , bronchoalveolar lavage , clinical endpoint , anesthesia , confidence interval , adverse effect , surgery , lung , randomized controlled trial , pathology , alternative medicine
Tumour necrosis factor receptor 1 (TNFR1) signalling mediates the cell death and inflammatory effects of TNF-α.