Open AccessInternal carotid artery blood flow is enhanced by elevating blood pressure during combined propofol-remifentanil and thoracic epidural anaesthesia
Author(s) -
Niels D. Olesen,
Hans Jørgen Frederiksen,
Jan Henrik Storkholm,
Carsten Palnæs Hansen,
Lars Bo Svendsen,
Niels Vidiendal Olsen,
Niels H. Secher
Publication year - 2020
Publication title -
european journal of anaesthesiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.445
H-Index - 76
eISSN - 1365-2346
pISSN - 0265-0215
DOI - 10.1097/eja.0000000000001189
Subject(s) - medicine , remifentanil , propofol , anesthesia , mean arterial pressure , internal carotid artery , cerebral blood flow , blood pressure , perfusion , hemodynamics , cerebral perfusion pressure , anastomosis , surgery , cardiology , heart rate
Anaesthesia reduces mean arterial pressure (MAP), and to preserve organ perfusion, vasopressors are often used to maintain MAP above 60 mmHg. Cognitive dysfunction is common following major surgery and may relate to intra-operative cerebral hypoperfusion.