Open AccessHypoxia, hypercarbia, and mortality reporting in studies of anaesthesia-related neonatal neurodevelopmental delay in rodent models
Author(s) -
Thomas F. Floyd,
Kseniya Khmara,
Ryan Lamm,
Peggy A. Seidman
Publication year - 2020
Publication title -
european journal of anaesthesiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.445
H-Index - 76
eISSN - 1365-2346
pISSN - 0265-0215
DOI - 10.1097/eja.0000000000001105
Subject(s) - hypercarbia , medicine , anesthesia , hypoxia (environmental) , neurotoxicity , general anaesthesia , toxicity , hypoxemia , chemistry , organic chemistry , oxygen
The concept of anaesthesia-related neonatal neurotoxicity originated in neonatal rodent models, yet prospective clinical studies have largely not supported this concern.