Open AccessProspective Association of 25-Hydroxyvitamin D3 and D2 with Childhood Lung Function, Asthma, Wheezing, and Flexural Dermatitis
Author(s) -
AnnaMaija Tolppanen,
Adrian Sayers,
Raquel Granell,
William D. Fraser,
John Henderson,
Debbie A. Lawlor
Publication year - 2013
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/ede.obo13e318280dd5e
Subject(s) - medicine , asthma , odds ratio , confidence interval , prospective cohort study , vital capacity , population , gastroenterology , lung , pediatrics , lung function , environmental health , diffusing capacity
Higher serum total 25-hydroxyvitamin D (25(OH)D) concentrations have been associated with better lung function and lower risk of allergic disease. 25(OH)D3 constitutes the majority of total 25(OH)D and has been suggested to be more potent than 25(OH)D2. We studied the prospective associations of 25(OH)D2 and 25(OH)D3 with asthma, wheezing, flexural dermatitis, and lung function in children who participated in the Avon Longitudinal Study of Parents and Children-a population-based contemporary birth cohort of children born in 1991-1992 from South West England.