Open AccessPapanicolaou Smears Induce Partial Immunity Against Sexually Transmitted Viral Infections
Author(s) -
Samuel Shapiro,
Margaret Hoffman,
Deborah Constant,
Lynn Rosenberg,
Henri Carrara,
Bruce Allan,
Dianne J. Marais,
JoAnn S. Passmore,
AnnaLise Williamson
Publication year - 2007
Publication title -
epidemiology
Language(s) - Uncategorized
Resource type - Journals
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/ede.0b013e31815774fc
Subject(s) - odds ratio , medicine , confidence interval , papanicolaou stain , obstetrics , cervical cancer , pap test , odds , gynecology , immunology , logistic regression , cancer , cervical cancer screening
In a case-control study of hormonal contraceptives and invasive cervical cancer, an unexpected finding was a substantial decline in the prevalence of high-risk human papillomavirus (HPV) infection according to the lifetime number of Pap smears received. Here we assess the risk of 3 sexually transmitted viral infections -- herpes simplex virus 2 (HSV2), HPV, and human immunodeficiency virus (HIV) 1 and 2 -- in relation to the lifetime receipt of Pap smears.