Open AccessA Prospective Study of Leukocyte Telomere Length and Risk of Gestational Diabetes in a Multiracial Cohort
Author(s) -
Yuan Lin,
Yeyi Zhu,
Jing Wu,
Stefanie Hinkle,
Shristi Rawal,
Jiali Han,
Natalie L. Weir,
Michael Y. Tsai,
Cuilin Zhang
Publication year - 2019
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/ede.0000000000001081
Subject(s) - gestational diabetes , odds ratio , medicine , confidence interval , pregnancy , prospective cohort study , obstetrics , gestational age , diabetes mellitus , logistic regression , cohort study , gestation , endocrinology , biology , genetics
Short telomere length (TL), an indicator of cellular aging and oxidative stress, has been implicated in glucose homeostasis. Additionally, studies have illustrated that the association of TL with health outcomes may vary by age. Yet, data on the association between TL and gestational diabetes mellitus (GDM) are sparse and the potential effect modification by age remains unknown.