Open AccessPerineal Talc Use, Douching, and the Risk of Uterine Cancer
Author(s) -
Katie M. O’Brien,
Aimee A. D’Aloisio,
Min Shi,
John D. Murphy,
Dale P. Sandler,
Clarice R. Weinberg
Publication year - 2019
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/ede.0000000000001078
Subject(s) - medicine , endometrial cancer , hazard ratio , talc , uterine cancer , prospective cohort study , gynecology , confidence interval , proportional hazards model , cohort study , cancer , cohort , hysterectomy , obstetrics , surgery , biology , paleontology
Perineal talc use and douching could affect the risk of uterine cancer through several possible pathways, including inflammation response, microbiota changes, or endocrine disruption. Two previous cohort studies of the association between talc use and uterine cancer have reported weak positive associations, but we know of no previous evaluations of the relationship between douching and uterine cancer.