Open AccessIs the Association Between Pregnancy Weight Gain and Fetal Size Causal?
Author(s) -
Jennifer A. Hutcheon,
Olof Stephansson,
Sven Cnattingius,
Lisa M. Bodnar,
Kari Johansson
Publication year - 2019
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/ede.0000000000000959
Subject(s) - weight gain , medicine , confounding , pregnancy , birth weight , small for gestational age , gestational age , obstetrics , body mass index , population , logistic regression , percentile , body weight , statistics , biology , mathematics , genetics , environmental health
Observational cohort studies have consistently shown that maternal weight gain in pregnancy is positively associated with fetal size, but it is unknown whether the association is causal. This study investigated the effect of pregnancy weight gain on fetal growth using a sibling comparison design to control for unmeasured confounding by genetic and shared environmental factors.