Open AccessMaternal Serum Paraxanthine During Pregnancy and Offspring Body Mass Index at Ages 4 and 7 Years
Author(s) -
Mark A. Klebanoff,
Sarah A. Keim
Publication year - 2015
Publication title -
epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.901
H-Index - 173
eISSN - 1531-5487
pISSN - 1044-3983
DOI - 10.1097/ede.0000000000000220
Subject(s) - paraxanthine , medicine , body mass index , pregnancy , odds ratio , obesity , obstetrics , gestation , confidence interval , offspring , biology , cyp1a2 , cytochrome p450 , metabolism , genetics
Obesity affects 18% of U.S. children. In a recent report, maternal consumption of ≥150 mg of caffeine per day during pregnancy was associated with increased odds for obesity in the offspring (odds ratio = 2.1 [95% confidence interval = 1.2-3.5]). If this association was causal, a considerable fraction of childhood obesity might be prevented by reduction of caffeine intake in pregnancy.