Open AccessEfficacy and Safety of 3 New Resilient Hyaluronic Acid Fillers, Crosslinked With Decreased BDDE, for the Treatment of Dynamic Wrinkles: Results of an 18-Month, Randomized Controlled Trial Versus Already Available Comparators
Author(s) -
Berthold Rzany,
Sophie Converset-Viethel,
Melanie Hartmann,
J.-C. Larrouy,
Natalia Ribé,
Giuseppe Sito,
Carole Noize-Pin
Publication year - 2019
Publication title -
dermatologic surgery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.659
H-Index - 125
eISSN - 1524-4725
pISSN - 1076-0512
DOI - 10.1097/dss.0000000000001971
Subject(s) - medicine , wrinkle , hyaluronic acid , randomized controlled trial , patient satisfaction , surgery , dermatology , gerontology , anatomy
Three new hyaluronic acid (HA)-based fillers made of long chains crosslinked with reduced amounts of 1,4-butanediol diglycidyl ether (BDDE) were developed for the treatment of dynamic facial areas. Their resilience and increased stretching ability were optimized to ease injectors' practice and provide patients with most natural aesthetic results.