Open AccessOrganoid Models of Colorectal Pathology: Do They Hold the Key to Personalized Medicine? A Systematic Review
Author(s) -
Reece K. DeHaan,
Samaneh K. Sarvestani,
Emina Huang
Publication year - 2020
Publication title -
diseases of the colon and rectum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 162
eISSN - 1530-0358
pISSN - 0012-3706
DOI - 10.1097/dcr.0000000000001806
Subject(s) - organoid , medicine , colorectal cancer , colorectal surgery , personalized medicine , disease , medline , precision medicine , pathology , bioinformatics , cancer , neuroscience , biology , abdominal surgery , biochemistry
Colorectal cancer and IBD account for a large portion of the practice of colorectal surgery. Historical research models have provided insights into the underlying causes of these diseases but come with many limitations.