Open AccessDifferential Expression of PEG10 Contributes to Aggressive Disease in Early Versus Late-Onset Colorectal Cancer
Author(s) -
Katherine M. Watson,
Ivy H. Gardner,
Raphael M. Byrne,
Rebecca Ruhl,
Christian Lanciault,
Elizabeth Dewey,
Sudarshan Anand,
Vassiliki L. Tsikitis
Publication year - 2020
Publication title -
diseases of the colon and rectum
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 162
eISSN - 1530-0358
pISSN - 0012-3706
DOI - 10.1097/dcr.0000000000001774
Subject(s) - colorectal cancer , medicine , oncology , cancer , age of onset , surgical oncology , disease
Colorectal cancer is a leading cause of cancer-related death. Early onset colorectal cancer (age ≤45 y) is increasing and associated with advanced disease. Although distinct molecular subtypes of colorectal cancer have been characterized, it is unclear whether age-related molecular differences exist.