Open AccessHow Large a Study Is Needed to Detect TKA Revision Rate Reductions Attributable to Robotic or Navigated Technologies? A Simulation-based Power Analysis
Author(s) -
Matthew D Hickey,
Carolyn Anglin,
Bassam A. Masri,
Antony J. Hodgson
Publication year - 2021
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1097/corr.0000000000001909
Subject(s) - medicine , randomized controlled trial , survivorship curve , comparative effectiveness research , psychological intervention , clinical trial , cohort , cohort study , arthroplasty , physical therapy , medical physics , physical medicine and rehabilitation , surgery , population , alternative medicine , environmental health , pathology , psychiatry
Robotic and navigated TKA procedures have been introduced to improve component placement precision in the hope of improving implant survivorship and other clinical outcomes. Although numerous comparative studies have shown enhanced precision and accuracy in placing components, most comparative studies have not shown that such interventions result in improved implant survival. Given what we know about effect sizes from large arthroplasty registries, large cohort studies, and large randomized controlled trials (RCTs), we wondered how large randomized trials would need to be to detect such small differences, and if the number is very high, what that would tell us about the value of these treatments for preventing revision surgery.