Open AccessAntibiotic Stewardship Interventions Improve Choice of Antibiotic Prophylaxis in Total Joint Arthroplasty in Patients with Reported Penicillin Allergies
Author(s) -
R. G. Gordon Jones,
Katelyn Quartuccio,
Judith M. Stern,
Eric Heintz,
Kelly E Pillinger,
Thomas G. Myers
Publication year - 2021
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1097/corr.0000000000001739
Subject(s) - medicine , cefazolin , penicillin , antibiotics , allergy , cephalosporin , adverse effect , intensive care medicine , pediatrics , surgery , immunology , biology , microbiology and biotechnology
Most patients who report a penicillin allergy can tolerate cefazolin, the preferred prophylaxis in a total joint arthroplasty (TJA). Regardless, patients with a reported penicillin allergy are less likely to receive first-line perioperative antibiotics as a result of inaccurate penicillin allergy documentation and misconceptions regarding cross-reactivity between penicillin and cephalosporins. The over-reporting of penicillin allergies and the safety of cephalosporins in patients with reported penicillin allergies have been well established throughout the evidence [13].