Open AccessEarly Antibiotic Administration Is Associated with a Reduced Infection Risk When Combined with Primary Wound Closure in Patients with Open Tibia Fractures
Author(s) -
David A. Zuelzer,
Christopher Hayes,
Gavin S Hautala,
Adam Akbar,
Ryan Mayer,
Cale A. Jacobs,
Raymond D. Wright,
Eric S. Moghadamian,
Paul E. Matuszewski
Publication year - 2020
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1097/corr.0000000000001507
Subject(s) - medicine , tibia , surgery , negative pressure wound therapy , antibiotics , clinical endpoint , orthopedic surgery , open fracture , anesthesia , randomized controlled trial , alternative medicine , pathology , microbiology and biotechnology , biology
Early administration of antibiotics and wound coverage have been shown to decrease the deep infection risk in all patients with Type 3 open tibia fractures. However, it is unknown whether early antibiotic administration decreases infection risk in patients with Types 1, 2, and 3A open tibia fractures treated with primary wound closure.