Open AccessPostoperative Administration of Alpha-tocopherol Enhances Osseointegration of Stainless Steel Implants: An In Vivo Rat Model
Author(s) -
M. Savvidis,
Kyriakos A. Papavasiliou,
Ioannis Taitzoglou,
Aggeliki Giannakopoulou,
Dimitrios Kitridis,
Nikiforos Galanis,
Ioannis S. Vrabas,
Eleftherios Tsiridis
Publication year - 2019
Publication title -
clinical orthopaedics and related research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.178
H-Index - 204
eISSN - 1528-1132
pISSN - 0009-921X
DOI - 10.1097/corr.0000000000001037
Subject(s) - osseointegration , medicine , malondialdehyde , implant , bone healing , saline , intramedullary rod , dentistry , oxidative stress , surgery , anesthesia
Alpha-tocopherol, a well-known antioxidative agent, may have a positive effect on bone formation during the remodeling phase of secondary fracture healing. Fracture healing and osseointegration of implants share common biological pathways; hence, alpha-tocopherol may enhance implant osseointegration.